With Notes 8.5 and Domino 8.5 you get a new database structure that support things like Design compression, database compression and DAOS (for servers). This will let you reduce the sizes of your Notes databases but 30% or more!.

You can set the parameters in your Database Properties (Notes 8.5.1 Dialog shown):
Image:Reduce the size of your Notes Databases

Here I have set the parameters for reduce size and best performance. This can take a lot of time to manually go through all the database properties, then you have to compact to see the results. Best part is that you can do this for workstation also! So now you can reduce the space used on your laptop!

Or you can do a compact with some parameters that will set the flags for you!

First make sure you have the following entry in your notes.ini file

If you have Notes 8.02 then use this parameter, but you can only get design compression (ODS 48):

Create_R8_Databases=1

For Design and data compression you need Notes 8.5, so you'll use this parameters:(ODS 51)

Create_R85_Databases=1

For window users, open a DOS command window in the Notes code folder and type:
ncompact -c -ZU -n -v

Here is what the prameters do:
-c        Copy style compact, used to put db in new ods format.
-ZU        Converts document attachments using compression type Huffman to LZ1 if db property is set.
-n        Compress design
-v        Compress data

After it's done you will have more room and faster access.